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Gilead Sciences, Inc.
  • Position Number: 2027869
  • Location: Foster City, CA
  • Position Type: Development and Fund Raising

Sr. Research Associate I, Process Development (Protein Purification) Oceanside CA
United States - California - Oceanside

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gileads therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the companys five core values. Thats because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

Sr. Research Associate I - Protein Purification Process Development

Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Together we deliver life-saving therapies to patients in need. With the commitment and drive you bring to the workplace every day, you will be part of a team that is changing the world and helping millions of people live healthier, more fulfilling lives. Our worldwide staff is a close community where you can see the tangible results of your contributions, where every individual matter, and everyone has a chance to enhance their skills through ongoing development. Our scientific focus has resulted in marketed products that are benefiting hundreds of thousands of people, a pipeline of late-stage drug candidates, and unmatched patient access programs to ensure medications are available to those who could otherwise not afford them.

By joining Gilead, you will further our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases.

Gilead Sciences is seeking a Sr. Research Associate I with experience in protein purification process development to support operations at our biologic's development and manufacturing site in Oceanside California.

Specific Responsibilities and skills for Position:
  • The successful candidate will have a working understanding of downstream process development including centrifugation, normal and tangential flow filtration, chromatography operations, and virus clearance.
  • The ability to demonstrate hands on experience in several of these areas is expected.
  • Experience with multiple modalities (monoclonal antibodies, antibody drug conjugates, virus particles) produced in microbial and mammalian expression systems is a plus.
  • The candidate is expected to work effectively within the purification team to help design and execute experiments supporting process definition, optimization, and characterization with an increasing level of independence.
  • The candidate will collaborate with Technical Operations during technology transfer from process development to GMP manufacturing, including serving as a process development representative during purification operations, providing technical trouble-shooting and identifying opportunities for future process and equipment improvements.
  • The candidate will also contribute to the preparation of regulatory filings and process validation and characterization reports.
  • The applicant should be an effective communicator of ideas, project goals and results and should have the ability to proactively identify issues and suggest solutions in a collaborative, multidisciplinary environment.
  • This is a highly collaborative environment where willingness and ability to communicate and work effectively with individuals across various teams is essential.
  • Candidates should be self-motivated, organized, and enjoy scientific investigation and thinking.
  • The candidate will monitor and contribute to external literature and scientific conferences.

Specific Job Responsibilities:

  • Plan and execute assigned experiments that support Process Development activities and project goals.
  • Select appropriate methods and techniques for performing experiments.
  • Develop skills in data analysis and interpreting experiment outcomes including the ability to evaluate data quality and recognize anomalous results.
  • Recommend alternatives, research new methods and techniques and proactively seek out senior personnel to discuss potential solutions to problems.
  • Participate in group meetings and present results, data interpretation and conclusions.
  • Demonstrate strong verbal communication and interpersonal skills including the ability to explain processes used to achieve results of assigned tasks.
  • Work with team oriented, collaborative and problem-solving mindset.
  • Always work with safety in mind.

Specific Education & Experience Requirements:
  • 2+ years of experience with BS degree in a relevant scientific discipline.
  • 0+ years of experience with MS degree in a relevant scientific discipline.

Preferred Training and Experience:
  • Chemical/Biochemical Engineering, Biochemistry, Chemistry or a related scientific discipline.
  • Prior experience in biologics purification, with an emphasis on affinity, IEX, and HIC.
  • Prior experience in analytical SEC/HPLC and CE (R/NR) is beneficial, but not required.
  • Knowledge of cGMPs, technology transfer, and scaling up bioprocesses.
  • Must be able to work effectively in cross-functional teams.
  • Must demonstrate excellent technical writing skills.

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.

For more information about equal employment opportunity protections, please view the EEO is the Law' poster.



Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

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